Aflibercept
- BNF:
- Eye
- Status:
- Do Not Prescribe (DNP), Red
- Decision Date:
- None
Comments
RED
- NICE TA294: injection for treating
wet age-related macular degeneration. (Decision date - August 2013)
- NICE TA305: for visual impairment
caused by macular oedema secondary to CRVO. (Decision date - March 2014)
- NICE TA346: for treating diabetic macular oedema. (Decision date - August 2015)
- NICE TA409: for visual impairment
caused by macular oedema after branch retinal vein occlusion. (Decision
date - October 2016)
- NICE TA486: for treating choroidal neovascularisation. (Decision date - December 2017).
Do Not Prescribe (DNP)
- NICE TA307: Aflibercept in
combination with irinotecan and fluorouracil-based therapy for treating
metastatic colorectal cancer that has progressed following prior
oxaliplatin-based chemotherapy. (Aflibercept can be funded through the cancer drug fund for this indication. Seek advice from the oncologist/haematologist). (Decision date - April 2014).
Black Drug Classifications
- 6: Have NICE guidance that recommends they should not be used
Red Drug Classifications
- 1: Requiring specialist assessment to enable patient selection, initiation and ongoing treating
- 2: Requiring long term on-going monitoring of efficacy by a specialist and not suitable for shared care
- 3: Requiring long term on-going monitoring of toxicity by a specialist (either because of difficulty in recognising side effects or high cost of investigations to identify toxicity)
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